\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c(\uc601\uc5b4: mesolimbic pathway) \ub610\ub294 \ubcf4\uc0c1 \uacbd\ub85c(\uc601\uc5b4: reward pathway)\ub294 \ub1cc\uc758 \ub3c4\ud30c\ubbfc \uacbd\ub85c \uc911 \ud558\ub098\uc774\ub2e4. \uc911\ub1cc\uc758 \ubc30\ucabd \ud53c\uac1c\ubd80\uc640 \uc804\ub1cc \uae30\uc800\ud575\uc758 \ubc30\ucabd \uc120\uc870\uccb4\ub97c \uc5f0\uacb0\ud55c\ub2e4. \ubc30\ucabd \uc120\uc870\uccb4\uc5d0\ub294 \uae30\ub310\ud575\uacfc \ud6c4\uac01\uacb0\uc808 \ub4f1\uc774 \ud3ec\ud568\ub41c\ub2e4.\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\uc5d0\uc11c \uae30\ub310\ud575\uc73c\ub85c\uc758 \ub3c4\ud30c\ubbfc \ubd84\ube44\ub294 \uc720\uc778\uc801 \ud604\uc800\uc131(incentive salience, \ubcf4\uc0c1 \uc790\uadf9\uc5d0 \ub300\ud55c \ub3d9\uae30\uc640 \uc695\uad6c)\uc744 \uc870\uc808\ud558\uace0 \uac15\ud654\uc640 \ubcf4\uc0c1\uc5d0 \uad00\ub828\ub41c \uc6b4\ub3d9 \uae30\ub2a5 \ud559\uc2b5\uc744 \ucd09\uc9c4\ud55c\ub2e4. \ub610\ud55c \uc8fc\uad00\uc801\uc778 \ucf8c\uac10\uc758 \uc778\uc2dd\uc5d0\ub3c4 \uc601\ud5a5\uc744 \uc904 \uac00\ub2a5\uc131\uc774 \uc788\ub2e4. \uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c \ubc0f \uadf8\uc5d0 \uc5f0\uacb0\ub41c \uae30\ub310\ud575 \uc2e0\uacbd\uc138\ud3ec\uc758 \uc870\uc808\uace4\ub780\uc740 \ud0d0\ub2c9\uc758 \ud615\uc131\uacfc \uc720\uc9c0\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4.<\/p>\n
\n== \uad6c\uc870 ==
\n\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\ub294 \ubc30\ucabd \ud53c\uac1c\ubd80(VTA)\uc5d0\uc11c \ubed7\uc5b4\ub098\uc640 \uae30\ub310\ud575(NAcc)\uacfc \ud6c4\uac01\uacb0\uc808\uc744 \ud3ec\ud568\ud558\ub294 \ubc30\ucabd \uc120\uc870\uccb4\ub85c \uac00\ub294 \ub3c4\ud30c\ubbfc\uc2e0\uacbd\uc138\ud3ec\ub4e4\uc758 \ubaa8\uc784\uc774\ub2e4. \ub1cc\uc790\uadf9\ubcf4\uc0c1\uc744 \ub9e4\uac1c\ud558\ub294 \uc2e0\uacbd \uacbd\ub85c\ub4e4\uc758 \ubaa8\uc784\uc778 \uc548\ucabd\uc55e\ub1cc\ub2e4\ubc1c\uc5d0 \uc18d\ud55c\ub2e4.\uc911\ub1cc\uc5d0 \uc704\uce58\ud55c \ubc30\ucabd \ud53c\uac1c\ubd80\ub294 \ub3c4\ud30c\ubbfc\u00b7GABA\u00b7\uae00\ub8e8\ud0d0\uc0b0 \uc2e0\uacbd\uc138\ud3ec\ub4e4\ub85c \uc774\ub8e8\uc5b4\uc838 \uc788\ub2e4. \uc774 \ubd80\uc704\uc758 \ub3c4\ud30c\ubbfc\uc2e0\uacbd\uc138\ud3ec\ub294 \ub300\ub1cc\ub2e4\ub9ac\uad50\ub1cc\ud575\uacfc \ub4f1\uac00\ucabd \ud53c\uac1c\ud575\uc758 \ucf5c\ub9b0\uc131\uc2e0\uacbd\uc138\ud3ec\ub85c\ubd80\ud130 \uc790\uadf9\uc744 \uc804\ub2ec\ubc1b\uace0, \uc804\uc804\ub450\uc5fd \ub4f1 \ub2e4\ub978 \ubd80\uc704\uc758 \uae00\ub8e8\ud0d0\uc0b0\uc2e0\uacbd\uc138\ud3ec\ub85c\ubd80\ud130\ub3c4 \uc790\uadf9\uc744 \ubc1b\ub294\ub2e4. \ubc30\ucabd \uc120\uc870\uccb4\uc5d0 \uc704\uce58\ud55c \uae30\ub310\ud575\uacfc \ud6c4\uac01\uacb0\uc808\uc740 \uc8fc\ub85c \uc911\uac04\ud06c\uae30 \uac00\uc2dc\ub274\ub7f0(MSN)\uc73c\ub85c \uc774\ub8e8\uc5b4\uc838 \uc788\ub2e4. \uae30\ub310\ud575\uc740 \uac01\uac01 \ubcc0\uc5f0\uae30\ub2a5\uacfc \uc6b4\ub3d9\uae30\ub2a5\uc5d0 \uad00\ub828\ub41c NAcc \uaecd\uc9c8(NAcc shell)\uacfc NAcc \ud575\uc2ec(NAcc core)\uc758 \ub450 \ubd80\ubd84\uc73c\ub85c \ub098\ub25c\ub2e4. \uae30\ub310\ud575\uc758 \uc911\uac04\ud06c\uae30 \uac00\uc2dc\ub274\ub7f0\uc740 \ubc30\ucabd \ud53c\uac1c\ubd80\uc758 \ub3c4\ud30c\ubbfc\uc2e0\uacbd\uc138\ud3ec\uc640 \ud574\ub9c8\u00b7\ud3b8\ub3c4\uccb4\u00b7\uc548\ucabd\uc804\uc804\ub450\uc5fd\uc758 \uae00\ub8e8\ud0d0\uc0b0\uc2e0\uacbd\uc138\ud3ec\ub85c\ubd80\ud130 \uc790\uadf9\uc744 \uc804\ub2ec\ubc1b\ub294\ub2e4. \uc774\ub7ec\ud55c \uc790\uadf9\uc744 \ubc1b\uace0 \ud65c\uc131\ud654\ub41c \uc911\uac04\ud06c\uae30 \uac00\uc2dc\ub274\ub7f0\uc740 \ubc30\ucabd \ucc3d\ubc31\ud575\uc73c\ub85c GABA\ub97c \ubd84\ube44\ud55c\ub2e4.<\/p>\n
\n== \uae30\ub2a5 ==
\n\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\ub294 \uc720\uc778\uc801 \ud604\uc800\uc131, \ub3d9\uae30\ubd80\uc5ec, \uac15\ud654\ud559\uc2b5, \uacf5\ud3ec \ub4f1\ub4f1 \uc5ec\ub7ec \uc778\uc9c0 \uacfc\uc815\uc744 \uc870\uc808\ud55c\ub2e4.\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\ub294 \ub3d9\uae30 \ubd80\uc5ec\uc758 \uc778\uc9c0\uc5d0 \uad00\uc5ec\ud55c\ub2e4. \uc774 \uacbd\ub85c\uc5d0 \ub3c4\ud30c\ubbfc\uc774 \uace0\uac08\ub418\uac70\ub098 \uadf8 \uc2dc\uc791 \ubd80\uc704\uc5d0 \ubcd1\ubcc0\uc774 \uc0dd\uae30\uba74, \ub3d9\ubb3c\uc774 \ubcf4\uc0c1\uc744 \uc5bb\uc73c\ub824 \ud589\ub3d9\ud558\ub294 \uc815\ub3c4\uac00 \uc904\uc5b4\ub4e0\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \uc950\uac00 \ub2c8\ucf54\ud2f4 \uc815\ub9e5 \uc8fc\uc785\uc744 \ubc1b\uc73c\ub824\uace0 \uc190\uc7a1\uc774\ub97c \ub204\ub974\ub294 \ud69f\uc218\ub098 \uba39\uc774\ub97c \ucc3e\uc73c\ub7ec \ub3cc\uc544\ub2e4\ub2c8\ub294 \uc2dc\uac04\uc774 \uac10\uc18c\ud558\ub294 \uac83\uc744 \uad00\ucc30\ud560 \uc218 \uc788\ub2e4. \ub3c4\ud30c\ubbfc\uc131 \uc57d\ubb3c\uc740 \ub3d9\ubb3c\uc774 \ubcf4\uc0c1\uc744 \uc5bb\uc73c\ub824 \ud589\ub3d9\ud558\ub294 \uc815\ub3c4\ub97c \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\ub2e4. \ub098\uc544\uac00, \ubcf4\uc0c1\uc744 \uae30\ub300\ud558\ub294 \ub3d9\uc548\uc5d0\ub294 \uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c \uc2e0\uacbd\uc138\ud3ec\uc758 \ubc1c\ud654\uc728\uc774 \uc99d\uac00\ud558\ub294\ub370, \uc774\ub294 \uac08\ub9dd(craving)\uc758 \uae30\uc804\uc5d0 \ub300\ud55c \uc124\uba85\uc774 \ub420 \uc218 \uc788\ub2e4. \uacfc\uac70\uc5d0 \uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\uc758 \ub3c4\ud30c\ubbfc \ubd84\ube44\ub294 \ucf8c\uac10\uc758 \uc8fc\ub41c \ub9e4\uac1c\uccb4\ub85c \uc0dd\uac01\ub418\uc5c8\uc73c\ub098, \ud604\uc7ac\ub294 \ucf8c\uac10\uc758 \uc9c0\uac01\uc5d0 \uc788\uc5b4 \uc911\ub1cc-\ubcc0\uc5f0\uacc4\uc758 \uc5ed\ud560\uc740 \ubd80\ucc28\uc801\uc77c \ubfd0\uc774\ub77c\uace0 \uc5ec\uaca8\uc9c4\ub2e4.<\/p>\n
\n== \uc784\uc0c1\uc801 \uc911\uc694\uc131 ==<\/p>\n
\n=== \ud0d0\ub2c9 \uae30\uc804 ===
\n\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\uc640 \uadf8 \ucd9c\ub825\uc744 \ubc1b\ub294 \ud2b9\uc815 \uc885\ub958\uc758 \uc2e0\uacbd\uc138\ud3ec(\uc608: \uae30\ub310\ud575\uc758 D1-\uc720\ud615 \uc911\uac04\ud06c\uae30 \uac00\uc2dc\ub274\ub7f0)\uc740 \ud0d0\ub2c9\uc758 \uc2e0\uacbd\uc0dd\ubb3c\ud559\uc5d0\uc11c \ud575\uc2ec \uc5ed\ud560\uc744 \ud55c\ub2e4. \uc57d\ubb3c \ud0d0\ub2c9\uc740 \uc2b5\uad00\uc801 \uc57d\ubb3c \uc0ac\uc6a9\uc5d0 \ub530\ub978 \ub1cc \uc2e0\uacbd\ud68c\ub85c\uc758 \ud654\ud559\uc801 \ubcc0\ud654 \ub54c\ubb38\uc5d0 \uc0dd\uae30\ub294 \ubcd1\uc774\ub2e4. \ucf54\uce74\uc778, \uc54c\ucf54\uc62c, \ub2c8\ucf54\ud2f4 \ub4f1 \ud754\ud788 \uc811\ud560 \uc218 \uc788\ub294 \uc911\ub3c5\uc131 \ubb3c\uc9c8\uc740 \uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c, \ud2b9\ud788 \uae30\ub310\ud575\uc5d0\uc11c \uc138\ud3ec\uc678 \ub3c4\ud30c\ubbfc \ub18d\ub3c4\ub97c \ub192\uc774\ub294 \uac83\uc73c\ub85c \ub4dc\ub7ec\ub0ac\ub2e4. \uadf8 \uae30\uc804\uc740 \uc57d\ubb3c\uc758 \uc720\ud615\uc5d0 \ub530\ub77c \ub2e4\ub974\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \ucf54\uce74\uc778\uc740 \uc2dc\ub0c5\uc2a4\uc804 \ub3c4\ud30c\ubbfc \uc804\ub2ec\uccb4\ub97c \ucc28\ub2e8\ud558\uc5ec \uc2dc\ub0c5\uc2a4 \ub3c4\ud30c\ubbfc\uc758 \uc7ac\ud761\uc218\ub97c \ub9c9\ub294\ub2e4. \ub610\ub2e4\ub978 \uc790\uadf9\uc81c\uc778 \uc554\ud398\ud0c0\ubbfc\uc740 \uc2dc\ub0c5\uc2a4\uc18c\ud3ec\uc758 \ub3c4\ud30c\ubbfc \ubd84\ube44\ub97c \ucd09\uc9c4\ud55c\ub2e4. \uc790\uadf9\uc81c\uac00 \uc544\ub2cc \uc57d\ubb3c\uc758 \uacbd\uc6b0 \ub9ac\uac04\ub4dc \uac1c\ud3d0 \ud1b5\ub85c\ub098 G \ub2e8\ubc31\uc9c8 \uc5f0\uacb0 \uc218\uc6a9\uccb4\uc640 \uacb0\ud569\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc740\ub370, \uc54c\ucf54\uc62c, \ub2c8\ucf54\ud2f4, \ud14c\ud2b8\ub77c\ud558\uc774\ub4dc\ub85c\uce74\ub098\ube44\ub180(THC) \ub4f1\uc774 \uadf8 \uc608\uc774\ub2e4.\uc774\ucc98\ub7fc \uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\uac00 \ud65c\uc131\ud654\ub418\uc5b4 \ub3c4\ud30c\ubbfc\uc744 \ubd84\ube44\ud558\uba74 \ubcf4\uc0c1\uc744 \uc778\uc9c0\ud558\uac8c \ub41c\ub2e4. \uc774\ub807\uac8c \ud615\uc131\ub41c \uc790\uadf9\uacfc \ubcf4\uc0c1\uc758 \uc5f0\uacb0\uc740 \uc18c\uac70\uc5d0 \uc800\ud56d\uc131\uc774 \uc788\uc73c\uba70, \ubcf4\uc0c1\uc744 \uc900 \ud589\ub3d9\uc744 \ub611\uac19\uc774 \ubc18\ubcf5\ud558\ub824\ub294 \ub3d9\uae30\uc758 \uc815\ub3c4\ub97c \ub192\uc778\ub2e4.2017\ub144\uc758 \ud55c \uc5f0\uad6c\ub294 \uac10\uc815\uc801\u00b7\uc2e0\uccb4\uc801\u00b7\uc131\uc801 \ud559\ub300\uc640 \ubd80\uc815\uc801 \uc0dd\uc560\uc0ac\uac74\uc740 \ucf54\uce74\uc778\uc5d0 \ub300\ud55c \ubcc0\uc5f0\uacc4\uc758 \ub192\uc740 \ubc18\uc751 \uc218\uc900\uacfc \uc0c1\uad00\uad00\uacc4\uac00 \uc788\ub2e4\uace0 \ubcf4\uace0\ud588\ub2e4. \uc989, \ud559\ub300\ub97c \uacbd\ud5d8\ud55c \uc0ac\ub78c\uc740 \ucf54\uce74\uc778 \ub4f1 \uc57d\ubb3c \uc0ac\uc6a9\uc5d0 \ube60\uc9c0\uae30 \uc26c\uc6b4 \ub1cc \uc2e0\uacbd\ud68c\ub85c\ub97c \uac00\uc9c8 \ud655\ub960\uc774 \ub354 \ub192\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n
\n=== \uc2e0\uacbd \ubc0f \uc2ec\ub9ac \uc7a5\uc560\uc640\uc758 \uad00\uacc4 ===
\n\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\ub294 \uc870\ud604\ubcd1, \uc6b0\uc6b8\uc99d, \ud30c\ud0a8\uc2a8\ubcd1\uacfc \uad00\ub828\uc774 \uc788\ub2e4. \ub610 \uc804\uc790 \ub9e4\uccb4 \uacfc\uc6a9\uc5d0\ub3c4 \uad00\ub828\ub3fc \uc788\ub2e4\ub294 \uc8fc\uc7a5\uc774 \uc788\ub2e4. \uac01\uac01\uc758 \uc7a5\uc560\ub294 \uc911\ub1cc-\ubcc0\uc5f0\uacc4\uc758 \uc11c\ub85c \ub2e4\ub978 \uad6c\uc870\uc801 \ubcc0\ud654\ub97c \ub3d9\ubc18\ud55c\ub2e4.<\/p>\n
\n== \ub2e4\ub978 \ub3c4\ud30c\ubbfc \uacbd\ub85c ==<\/p>\n
\uc911\ub1cc-\ud53c\uc9c8 \uacbd\ub85c
\n\ud751\uc0c9\uc9c8-\uc120\uc870\uccb4 \uacbd\ub85c
\n\uacb0\uc808-\ub204\ub450\uccb4 \uacbd\ub85c<\/p>\n
\n== \uac19\uc774 \ubcf4\uae30 ==
\n\ud56d\uc815\uc2e0\ubcd1\uc81c\uc81c
\n\uc9c0\uc5f0\uc131 \uc6b4\ub3d9\uc7a5\uc560
\n\ub0b4\uc131 (\uc57d\ubb3c)
\n\uae08\ub2e8 \uc99d\uc0c1<\/p>\n
\n== \uac01\uc8fc ==<\/p>\n
\n== \uc678\ubd80 \ub9c1\ud06c ==<\/p>\n","protected":false},"excerpt":{"rendered":"
\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c(\uc601\uc5b4: mesolimbic pathway) \ub610\ub294 \ubcf4\uc0c1 \uacbd\ub85c(\uc601\uc5b4: reward pathway)\ub294 \ub1cc\uc758 \ub3c4\ud30c\ubbfc \uacbd\ub85c \uc911 \ud558\ub098\uc774\ub2e4. \uc911\ub1cc\uc758 \ubc30\ucabd \ud53c\uac1c\ubd80\uc640 \uc804\ub1cc \uae30\uc800\ud575\uc758 \ubc30\ucabd \uc120\uc870\uccb4\ub97c \uc5f0\uacb0\ud55c\ub2e4. \ubc30\ucabd \uc120\uc870\uccb4\uc5d0\ub294 \uae30\ub310\ud575\uacfc \ud6c4\uac01\uacb0\uc808 \ub4f1\uc774 \ud3ec\ud568\ub41c\ub2e4.\uc911\ub1cc-\ubcc0\uc5f0\uacc4 \uacbd\ub85c\uc5d0\uc11c \uae30\ub310\ud575\uc73c\ub85c\uc758 \ub3c4\ud30c\ubbfc \ubd84\ube44\ub294 \uc720\uc778\uc801 \ud604\uc800\uc131(incentive salience, \ubcf4\uc0c1 \uc790\uadf9\uc5d0 \ub300\ud55c \ub3d9\uae30\uc640 \uc695\uad6c)\uc744 \uc870\uc808\ud558\uace0 \uac15\ud654\uc640 \ubcf4\uc0c1\uc5d0 \uad00\ub828\ub41c \uc6b4\ub3d9 \uae30\ub2a5 \ud559\uc2b5\uc744 \ucd09\uc9c4\ud55c\ub2e4. \ub610\ud55c \uc8fc\uad00\uc801\uc778 \ucf8c\uac10\uc758 \uc778\uc2dd\uc5d0\ub3c4 \uc601\ud5a5\uc744 \uc904 \uac00\ub2a5\uc131\uc774 […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=\/wp\/v2\/posts\/280"}],"collection":[{"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=280"}],"version-history":[{"count":1,"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=\/wp\/v2\/posts\/280\/revisions"}],"predecessor-version":[{"id":281,"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=\/wp\/v2\/posts\/280\/revisions\/281"}],"wp:attachment":[{"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=280"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/testpie.com\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}